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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAV2 All Species: 13.03
Human Site: Y27 Identified Species: 31.85
UniProt: P51636 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51636 NP_001224.1 162 18291 Y27 S H H S G L E Y A D P E K F A
Chimpanzee Pan troglodytes XP_001136349 211 22753 P76 P S L L L P P P E A L P V P G
Rhesus Macaque Macaca mulatta NP_001162090 162 18233 Y27 S H H S G L E Y A D P E K F A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WVC3 162 18209 Y27 S H H S G V D Y A D P E K Y V
Rat Rattus norvegicus Q2IBC5 162 18248 Y27 S H H S V V D Y T D P E K Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus Q07E02 178 20361 Y42 D L P E K Q L Y D A H T K E I
Chicken Gallus gallus P35431 178 20428 H42 E L S E K A V H D V D T K E I
Frog Xenopus laevis NP_001082298 160 18261 L27 N H S T V P M L T E K T F D N
Zebra Danio Brachydanio rerio NP_001002150 162 18519 L27 N R S I E P I L G K K P N V Y
Tiger Blowfish Takifugu rubipres Q9YGM9 162 18218 L27 N R S I E P I L S K K A R L Y
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 60.1 97.5 N.A. N.A. 90.1 88.8 N.A. 33.1 30.8 64.8 51.2 48.7 N.A. N.A. N.A. N.A.
Protein Similarity: 100 63.9 98.1 N.A. N.A. 95 94.4 N.A. 53.9 52.8 78.4 72.2 68.5 N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 N.A. N.A. 73.3 60 N.A. 13.3 6.6 6.6 0 0 N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 N.A. N.A. 93.3 80 N.A. 13.3 13.3 26.6 6.6 20 N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 30 20 0 10 0 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 20 0 20 40 10 0 0 10 0 % D
% Glu: 10 0 0 20 20 0 20 0 10 10 0 40 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 20 0 % F
% Gly: 0 0 0 0 30 0 0 0 10 0 0 0 0 0 10 % G
% His: 0 50 40 0 0 0 0 10 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 20 0 0 20 0 0 0 0 0 0 0 20 % I
% Lys: 0 0 0 0 20 0 0 0 0 20 30 0 60 0 0 % K
% Leu: 0 20 10 10 10 20 10 30 0 0 10 0 0 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 30 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % N
% Pro: 10 0 10 0 0 40 10 10 0 0 40 20 0 10 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 20 0 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 40 10 40 40 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 0 20 0 0 30 0 0 0 % T
% Val: 0 0 0 0 20 20 10 0 0 10 0 0 10 10 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 20 20 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _